¾ÛºÏÎコÊø£¨OPDEA-PDCA£©

¾ÛºÏÎコÊø£¨OPDEA-PDCA£©

¡¾Numbering¡¿BKMC102000 ¡¾CAS¡¿CAS
¡¾Item No.¡¿BKMC102000-2 ¡¾specification¡¿
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Name: Polymer micelles (OPDEA-PDCA)
Composition: OPDEA, DCA
Size: 100-200nm
Application: Mitochondrial targeting, pyroptosis and anti-tumor
Storage conditions: -4¡æ
Other instructions: Half year shelf life under sealed state [main advantages] 1. OPDEA-PDCA targets mitochondria and induced mitochondrial oxidative stress by inhibiting PDHK 1, leading to immunogenic pyroptosis of osteosarcoma cell lines; 2. Researchers found that OPDEA-PDCA can induce the secretion of soluble programmed cell death ligand 1 (PD-L1) molecule; 3. OPDEA-PDCA and anti-PD-L1 monoclonal antibody combination treatment can significantly inhibit osteosarcoma proliferation and prolong T cell activation.
Title:Mitochondria-Targeting Polymer Micelle of Dichloroacetate Induced Pyroptosis to Enhance Osteosarcoma Immunotherapy
Article link:http://www.nanoer.net/showinfo-4-43326.html



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