PFG-MPN
| 【Numbering】BKMC106011 | 【CAS】CAS | ||
| 【Item No.】BKMC106011-2 | 【specification】 | ||
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Name: PFG-MPN
Composition: Phenolic polymers + PEG polymer + GW 4869
Grain size: 50-200nm
Application: Ion visual sensing
Storage conditions: -4℃
Other instructions: shelf life of half a year in sealed state [Main advantages] PFG-MPN, as a good structural motif, can effectively form mpn carrying therapeutic drugs through metal-phenol coordination, with unique characteristics (such as rapid coordination process, excellent metal chelation ability and pH responsiveness). Phototherapeutic mpn (PFGMPNs) was achieved by encapsulating the hydrophobic-exosome inhibitor GW4869 into the core of PFG-MPN. After tumor accumulation, PFG-MPN with superior NIR II fluorescence / photoacoustic imaging performance upon NIR laser irradiation can generate heat for PTT induction, release DAMPs and promote good maturation of dendritic cells. Exosome depletion of GW 4869 can break the restriction of T cell function by exosomal PD-L1. The recovered T cytocause
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Composition: Phenolic polymers + PEG polymer + GW 4869
Grain size: 50-200nm
Application: Ion visual sensing
Storage conditions: -4℃
Other instructions: shelf life of half a year in sealed state [Main advantages] PFG-MPN, as a good structural motif, can effectively form mpn carrying therapeutic drugs through metal-phenol coordination, with unique characteristics (such as rapid coordination process, excellent metal chelation ability and pH responsiveness). Phototherapeutic mpn (PFGMPNs) was achieved by encapsulating the hydrophobic-exosome inhibitor GW4869 into the core of PFG-MPN. After tumor accumulation, PFG-MPN with superior NIR II fluorescence / photoacoustic imaging performance upon NIR laser irradiation can generate heat for PTT induction, release DAMPs and promote good maturation of dendritic cells. Exosome depletion of GW 4869 can break the restriction of T cell function by exosomal PD-L1. The recovered T cytocause
Title:Phototheranostic Metal-Phenolic Networks with Antiexosomal PDL1 Enhanced Ferroptosis for Synergistic Immunotherapy
Article link:https://pubs.acs.org/doi/10.1021/jacs.1c09753
| Warm tips: Suzhou Beike nano products are only used for scientific research, not for human body,different batches of products have different specifications and performance |
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