NPs/RSL3@AAGel
| 【Numbering】BKMC106004 | 【CAS】CAS | ||
| 【Item No.】BKMC106004-2 | 【specification】 | ||
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Name: NPs / RSL 3 @ AAGel
Composition: Zn0.4Fe2.6O4 Nanocube + RSL 3 + AAGel particle size: 30-100nm
Application: anti-tumor
Storage conditions: -4℃
Other instructions: shelf life of half a year in sealed state [Main advantages] The high magnetic heat conversion efficiency of nanocube and the application of echo restriction effect avoid MRI artifacts during MHT. In addition to the function of magnetic heating, the Zn0.4Fe2.6O4 nanobube combined with multiplex MHT can continuously supply redox-active iron to produce reactive oxygen species and lipid peroxides, accelerating the release of RLS 3 from AAGel and thereby enhancing the antitumor efficacy of ferrites. In turn, intensified ferrophagtosis can relieve tumor heat resistance triggered by MHT by impairing protective HSP 70. This synergistic strategy achieved the complete elimination of CT-26 tumors in mice without causing local tumor recurrence and other serious side effects.
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Composition: Zn0.4Fe2.6O4 Nanocube + RSL 3 + AAGel particle size: 30-100nm
Application: anti-tumor
Storage conditions: -4℃
Other instructions: shelf life of half a year in sealed state [Main advantages] The high magnetic heat conversion efficiency of nanocube and the application of echo restriction effect avoid MRI artifacts during MHT. In addition to the function of magnetic heating, the Zn0.4Fe2.6O4 nanobube combined with multiplex MHT can continuously supply redox-active iron to produce reactive oxygen species and lipid peroxides, accelerating the release of RLS 3 from AAGel and thereby enhancing the antitumor efficacy of ferrites. In turn, intensified ferrophagtosis can relieve tumor heat resistance triggered by MHT by impairing protective HSP 70. This synergistic strategy achieved the complete elimination of CT-26 tumors in mice without causing local tumor recurrence and other serious side effects.
Title:An injectable and active hydrogel induces mutually enhanced mild magnetic hyperthermia and ferroptosis
Article link:https://www.sciencedirect.com/science/article/pii/S0142961223001473
| Warm tips: Suzhou Beike nano products are only used for scientific research, not for human body,different batches of products have different specifications and performance |
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| Warm tips: Suzhou Beike nano products are only used for scientific research, not for human body,different batches of products have different specifications and performance.The website pictures are from the Internet. The pictures are for reference only. Please take the real object as the standard. In case of infringement, please contact us to delete them immediately. |
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