NH2-MIL-88（Fe）
| 【Numbering】BKMC105000 | 【CAS】CAS | ||
| 【Item No.】BKMC105000-2 | 【specification】 | ||
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Name: NH2-MIL-88 (Fe)
Composition: NH2-MIL-88 (Fe)
Grain size: ~200nm
Application: Peroxidase-like activity, catalysis and coordinated autophagy to inhibit cancer
Storage conditions: -4℃
Other instructions: the shelf life of half a year under the sealed state [main advantages] 1. Using the autophagy inhibition strategy to enhance the oxidative damage induced by reactive oxygen species, For the synergistic treatment of cancer; 2. The [MOF (Fe)] nanocatalyst prepared by simulated peroxidase, Catalyze the generation of highly oxidative OH within cancer cells, Where chloroquine is used to deacid lysosomes and inhibit autophagy, Cut off the self-protection pathway under severe oxidative stress; 3, during the nanocatalytic treatment, Cancer cells are unable to detoxify and enhance their own function by extracting their components, Eventually yielding to the ROS-induced oxidative damage; 4, in vitro and in vivo experiments demonstrating a synergistic effect between nanocatalytic therapy and autophagy inhibition, This combined strategy could be used to amplify tumor-specific oxidative damage.
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Composition: NH2-MIL-88 (Fe)
Grain size: ~200nm
Application: Peroxidase-like activity, catalysis and coordinated autophagy to inhibit cancer
Storage conditions: -4℃
Other instructions: the shelf life of half a year under the sealed state [main advantages] 1. Using the autophagy inhibition strategy to enhance the oxidative damage induced by reactive oxygen species, For the synergistic treatment of cancer; 2. The [MOF (Fe)] nanocatalyst prepared by simulated peroxidase, Catalyze the generation of highly oxidative OH within cancer cells, Where chloroquine is used to deacid lysosomes and inhibit autophagy, Cut off the self-protection pathway under severe oxidative stress; 3, during the nanocatalytic treatment, Cancer cells are unable to detoxify and enhance their own function by extracting their components, Eventually yielding to the ROS-induced oxidative damage; 4, in vitro and in vivo experiments demonstrating a synergistic effect between nanocatalytic therapy and autophagy inhibition, This combined strategy could be used to amplify tumor-specific oxidative damage.
Title:A Metal-Organic Framework (MOF) Fenton Nanoagent-Enabled Nanocatalytic Cancer Therapy in Synergy with Autophagy Inhibition
Article link:https://zhuanlan.zhihu.com/p/107375444
| Warm tips: Suzhou Beike nano products are only used for scientific research, not for human body,different batches of products have different specifications and performance |
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| Warm tips: Suzhou Beike nano products are only used for scientific research, not for human body,different batches of products have different specifications and performance.The website pictures are from the Internet. The pictures are for reference only. Please take the real object as the standard. In case of infringement, please contact us to delete them immediately. |
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